primary bone marrow

Objective : To investigate primary disease, pathogenesis, clinical feature and prognosis of bone marrow necrosis ( BMN ).

目的: 探讨骨髓坏死 ( BMN ) 的原发病 、 发病机理 、 临床特点及预后.

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Objective To study the effect of simvastatin on the expression of bone morphogenetic protein 2 ( BMP 2) and alkaline phosphates ( ALP) activity in the primary cultured bone marrow stromal cells, and to elucidate the mechanism of the anabolic osteogenetic effect of simvastatin.

目的研究辛伐他汀对原代培养的骨髓基质细胞骨形成蛋白-2（BMP-2）表达及碱性磷酸酶活性的影响，探讨其刺激成骨的作用机制。

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RESULTS: ① Growth, proliferation and morphological changes of rabbit bone marrow stromal cells cultured in vitro: A large amount of suspended round cells with clear outline were seen after primary culture.

结果：①兔骨髓基质细胞体外培养生长增殖及形态变化：原代培养细胞接种后见大量悬浮呈圆形的细胞，轮廓清晰。

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rarely the condition is caused by a primary bone marrow disorder.

该疾病极少由原发性骨髓异常引起。

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Results: Autogenous bone marrow-derived MSC showed active proliferative capacity in vitro in primary and passage cultures.

结果: 原代培养及传代培养显示,兔自体骨髓间充质干细胞具有活跃的增殖倍增能力.

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